CISC 472/3.0 Medical Informatics

Original Author: Purang Abolmaesumi
Last Revised: November 6, 2013

Calendar Description

Current topics in the application of information technology to medical image computing and its use in image-guided medical interventions.
Learning Hours: 120 (36L;84P)

Prerequisites: (CISC 271/3.0 or MATH-272/3.0) and CISC-330/3.0


This course provides an introduction to computational approaches to the use of medical imaging in computer-assisted surgery and interventions.

This course is required in the Biomedical Computing (BMCO) program.


  • Recap on medical image modalities (X-ray, CT, ultrasound and MRI)

  • Recap on tracking, coordinate system transformations, navigation, and basics of image-guided interventions

  • Rigid marker registration, iterative closest point (ICP)

  • Image formation

  • Filters

  • Segmentation

  • Similarity measures

  • Optimizers

  • Image registration (2D-2D, 3D-3D, 2D-3D)

  • Deformable registrations

  • Use of the above in image-guided intervention systems

Possible Texts

  • T. Peters and K. Cleary: Image-Guided Interventions: Technology and Applications, Springer 2008.

  • W. Birkfellner: Applied Medical Image Processing: A Basic Course, Taylor and Francis 2011.

  • Anthony Brinton Wolbarst: Looking Within: How X-Ray, Ct, MRI, Ultrasound, and Other Medical Images Are Created, and How They Help Physicians Save Lives, University of California Press 1999.

  • Bettyann Kevles: Naked to the Bone: Medical Imaging in the Twentieth Century, Perseus Publishing 1997.